Phalanx Biotech Group

Spot

Do More.

Understand More.

OneArray™

Welcome to Spot, Phalanx Biotech's monthly guide to getting the most out of your microarray experiments.

February 2008

 

 

Spot_Feb_2008.jpg

logo.jpgIn this month’s issue…

What’s new with OneArray™:

Take the OneArray $2000 Challenge >>Learn more

Annotation Pipeline shows OneArray’s excellent interrogation power

Phalanx Biotech Launches New Website

Technical Support / Application Scientist positions available

Ask Spot:

Can I use the Corning® Hybridization Chamber with OneArray?

What target controls can I use with OneArray?

Can I use my current protocol with OneArray microarrays?

 

What’s New

Phalanx Biotech Group Annotation Pipeline Shows Human OneArray’s Excellent Interrogation Power.

 

In an effort to investigate how to generate a more complete probe set, a probe annotation pipeline has been developed using the whole genome as a reference set. Analysis of available human gene expression microarrays indicates increased probe density does not correlate with increased gene coverage or interrogation power.

 

The annotation pipeline was used to evaluate probe sets from several different sources. Probes were assigned to six different categories based on their alignment to the whole genome.

The breakdown for the probe sets investigated (Figure 1) indicates sets with high probe density have a large amount of probe space dedicated to intergenic material (orange).
Further analysis indicates a high level of redundancy in gene coverage (Figure 2, grey). High probe density does not necessarily correlate with good gene coverage.

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Figure 1. Probe Set Breakdown

 

intpwr.jpg 

Figure 2. Interrogation Power

Visit our website to find out more about the Power of OneArray and read the complete Annotation TechNote (pdf download).

 

Phalanx Biotech launches new website.  Phalanx Biotech has launched its new website featuring:

A more user-friendly home page

Easier access to gene lists and probe annotation

A growing list of satisfied customers

Expanded customer support site, including experimental controls, troubleshooting guide, and FAQs

Please have a look. As always, we welcome your feedback and suggestions.

 

Phalanx Biotech is hiring.  Phalanx Biotech Group has immediate openings for recent PhD graduates for Technical Support Representatives/Application Scientists.  We are seeking energetic and “people friendly” individuals with microarray expertise who are inspired to develop a career in biotech sales and marketing. Email your CV to spot@phalanxbiotech.com or fax to 650-320-8488. 

Ask Spot:                                                          

Can I use Corning® Microarray Hybridization Chambers with OneArray?

Spot says: Yes. The Corning Microarray Hybridization Chambers are fully compatible with Human and Mouse OneArray whole genome microarrays.

What target controls can I use with OneArray?

Spot says: Both Human and Mouse OneArray contain control probes for monitoring your labeling, hybridization and scanning. These include Ambion ArrayControl™ RNA SPIKE #1~8 on both products. For more information on these and other experimental controls, please visit our products page.

Can I adapt my current protocol for use with OneArray?

Spot says: Users have had great success in adapting their established hybridization protocols for use with OneArray. The open format of OneArray is conducive to a variety of different protocols. Contact our technical support team for help in adapting your protocol.

Take the OneArray $2000 Challenge*

Try our human or mouse OneArray whole genome microarrays or gene expression profiling service. If you are not completely satisfied, it is free.

We challenge you to try OneArray whole genome microarrays or hybridization service and experience for yourself the Power of OneArray.

                        

Services and Products included in this Offer

Cost

8 Samples Dual Dye Microarray Service or

$2,000 + S&H

4 Samples Single Dye Microarray Service or

$1,400 + S&H

10 Human or Mouse OneArrays

$890 + S&H

 

*Offer valid only in North America and Taiwan. $2000 refers to US dollar and to the 8 samples of Dual Dye Microarray Service HDP_0022 or MDP_0022.

  Feedback

If you have any questions you would like answered, or would like tips on other aspects of gene expression profiling using OneArray, please Email us at spot@phalanxbiotech.com.

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Phalanx Biotech Group, Inc.

Ph:  650-320-8669

Hours of Operation:

1400 Page Mill Road

Fax: 650-320-8488

Monday – Friday, 8:30 am – 5:00 pm PST

Building B

Palo Alto, CA  94304

http://www.OneArray.com

 

OneArray™, Human OneArray™, and Mouse OneArray™ are trademarks of Phalanx Biotech Group, Inc. in the United States and other countries. All trademarks and copyrights used in this publication belong to their respective owners and are the sole property of their respective owners.

©2008 Phalanx Biotech Group, Inc.