The term “bioinformatics” has gained popularity over the past decade. Bioinformatics is a word used to describe the type of computational analysis carried out on datasets from biological science studies. Bioinformatics is an important step in a genomic experiment. However, the significance of this step is often lost due to the broad context in which […]
ChIP-Seq and Analysis
ChIP-seq (Chromatin Immunoprecipitation Sequencing) is a method that combines the DNA linked proteome information obtained from IP with next-generation sequencing. Most commonly, ChIP-seq is used to identify regions of the genome that are targeted by transcription factors or analyze histone/chromatin modifications. ChIP-seq can also be used in conjunction with other methods to provide insight into […]
Whole Exome Sequencing – The Whole Story
Rising Popularity of Whole Exome Sequencing and Whole Genome Sequencing Whole exome sequencing and whole genome sequencing (and the Bioinformatics to go along with them) seem to be the “It” topics. They were a major focus at many of the large Genomic and Biotechnology shows this year (including BIO International 2017 and The Festival of […]
Transcriptome Sequencing – Applications and Preparation
One of the most common uses for RNA Sequencing (RNA-Seq) is gene expression analysis (sometimes referred to as mRNA-Seq). However, there are many other types of RNA-Seq that can be used to address various research questions. Some other types of RNA-Seq include whole transcriptome sequencing, small RNA-Seq, single cell RNA-Seq and low-input RNA-Seq. The type […]
Gene Expression Analysis: RNA-Seq vs. Microarray
This infographic from Phalanx Biotech gives an overview of two widely used methods of gene expression analysis: RNA-Seq and Microarray. See below for the pros and cons of each. Microarrays have long been the method of choice for expression analysis. They are a proven method for affordable and reliable data acquisition. The microarray genomic platform […]
Phalanx Biotech takes on NGS!
How to select a Genomic Service Provider Whether you’re interested in transcript discovery, gene expression analysis, population genomics or genome assembly, deciding which company to entrust with your NGS samples can be a daunting task. The NGS market is booming and a quick Google search of facilities that provide genomic preparation and analysis will probably […]