Research Highlight: Adipose-Derived Stem Cells and Chemoresistance in Breast Cancer This month’s study focuses on triple negative breast cancer (TNBC) and how mesenchymal stem cells in the tumor microenvironment can influence therapeutic responses. We’re excited to feature an article from the lab of Dar-Ren Chen… [Read more]
TUNICAMYCIN, ER STRESS, AND CELL DEATH IN A PROSTATE CANCER CELL MODEL
This month we’re excited to feature an article from the lab of Hafiz Ahmed and others at the University of Maryland, School of Medicine involving the treatment of PC-3 prostate cancer cells with tunicamycin. The article was published 15 July 2017 in the journal Oncotarget… [Read more]
THE ROLES OF IGF-1, CYTOKINES, and miR-181D IN GLIOBLASTOMA PROGRESSSION
Introduction This month’s study focuses on the role of IGF-1, Cytokines, and miR-181D in Glioblastoma progression, and comes from the lab of Ku-Chung Chen and others at Taipei Medical University in Taiwan. The article was published 7 April 2017 in the journal Scientific Reports and… [Read more]
MICRORNA DYSREGULATION IN EGFR EXON 19 DELETION LUNG CANCER
MicroRNA Dysregulation in EGFR Exon 19 Deletion Lung Cancer This month’s study focuses on microRNA dysregulation in EGFR Exon 19 Deletion, and its role in lung cancer, using the Human OneArray® MicroRNA, conducted at the Phalanx Biotech Lab. We feature an article from Lixia Ju and… [Read more]
Methamphetamine-Induced Gene Expression Changes in Astrocytes
Study of Gene Expression Changes in Astrocytes Using Agilent Gene Expression Microarray at the Phalanx Biotech Service Lab. We’re happy to report on a paper that takes a systems biology approach to understanding how astrocytes respond to amphetamines. This study is from the lab of… [Read more]
Drug-resistant Small Cell Lung Cancer Research
This month’s featured article is from the lab of Longbang Chen of Nanjing University School of Medicine in Nanjing, China. The article was published 31 Mar 2017 in the journal Oncology Letters. This study focused on drug-resistant small cell lung cancer (SCLC), and more specifically,… [Read more]
OneArray® Research Highlight: Mechanisms of Adipocyte-Mediated Breast Cancer Progression – Nature Communications
This month’s featured article is from the lab of Wen-Hwa Lee at China Medical University in Taiwan and colleagues at National Taiwan University. The article about breast cancer research was published 10 Mar 2017 in the journal Nature Communications. This study focused on adipocytes in… [Read more]
OneArray® Research Highlight: Long Non-Coding RNA HOTAIR, miR-454-3p, and Their Role in Chondrosarcoma Tumor Growth
This month’s featured article is from the lab of Wei Guo of Peking University People’s Hospital in Beijing, China. The article was published in the February 2017 issue of the journal Cell Death and Disease. This study focused on the mechanistic roles of long non-coding… [Read more]
OneArray® Research Highlight: Androgen-Receptor-Mediated miRNA Expression During Breast Cancer
This month’s featured article is from the lab of Xiaoxiang Guan of Nanjing University in Nanjing, China. The article was published in the January 2017 issue of the journal Molecular Medicine Reports. This study focused on whether miRNAs have an effect on androgen receptor (AR)… [Read more]
OneArray® Research Highlight: Mechanisms of Light-Induced Apoptosis in Retinal Pigmented Epithelial Cells
This month’s featured article is from the labs of Z-B Jin and F Lu of the Lab for Stem Cells and Retinal Regeneration at Wenzhou Medical University in Wenzhou, China. The article was published 29 February 2016 in the journal Cell Death Discovery. This study… [Read more]
OneArray® Research Highlight: Characterization and Therapeutic Potential of Mesp1 Cardiac Progenitor Cells
This month’s featured article is from the labs of Robert Schwartz and Bradley McConnell of the University of Houston in Houston, Texas. The article was published 19 August 2016 in the journal Scientific Reports. This study investigates early embryonic stem cells expressing Mesp1. These cells… [Read more]
OneArray® Research Highlight: microRNA-mediated cardiomyocyte differentiation
This month’s featured article is from the labs of Robert Schwartz and Yu Liu of the University of Houston in Houston, Texas. The article was published 23 August 2016 in the journal PNAS. This study investigates the mechanisms of early cardiac fate determination. Understanding the… [Read more]
OneArray® Research Highlight: How miR-146a Mediates Angiogenesis in Human Endothelial Cells
This month’s featured article is from the labs of Hong-tao Wang and Da-hai Hu of Fourth Military Medical University in Xi’an, China. The article about human endothelial cell research was published 28 April 2016 in the journal Scientific Reports. This study investigates the cell signaling… [Read more]
OneArray® Research Highlight: How Lung Cancer Cells Immediately Respond to Targeted Therapy and Thereby Develop Drug Resistance
This month’s featured article is from the lab of John T-A Hsu of National Chiao Tung University in Hsinchu, Taiwan. The article regarding research on lung cancer cells was published 19 May 2016 in the journal OncoTargets and Therapy. This study investigates how non-small cell… [Read more]
OneArray® Research Highlight: The Mechanisms of Activity of a Milk-Derived Anti-Cancer Fusion Peptide
This month’s featured article is from the lab of Yide Qin of Anhui Medical University in Hefei, China. The article was published 24 March 2016 in the journal BMC Cancer. This study investigates the anti-cancer function and mechanisms of action of a milk-derived anti-cancer fusion… [Read more]
OneArray® Research Highlight: Mining Microarray Data for Diagnostic Indicators of Active and Latent Tuberculosis Infection
This month’s featured article is from a research group led by Julia Tzu-Ya Weng at Yuan Ze University in Taoyuan, Taiwan. The article was published on 11 January 2016 in the journal BMC Bioinformatics, based on findings first reported at the 14th Asia Pacific Bioinformatics… [Read more]
OneArray® Research Highlight: A Novel Molecular Therapeutic Targeting Hepatocellular Carcinoma
This month’s featured article is from a research group led by Pei-Ming Yang at Mackay Memorial Hospital in Taipei, Taiwan. The article was published on 29 January 2016 in the journal Oncoscience. This study investigates the potential of GSK343, an inhibitor to EZH2, as a… [Read more]